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Dingxi Liu, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

In vitro efficacy of TP-10@CaP-CTP in attenuating adult mouse CM (AMCM) pathological hypertrophy Pathological cardiac hypertrophy is a critical pathological condition that precedes heart failure 28,29

Studies in patients with type 2 diabetes and obesity have demonstrated that the use of SGLT2 inhibitors, particularly empagliflozin, not only increases overall cancer risk but also significantly elevates the risk of bladder cancer [10, 108]

The same mechanism that extends the replicative life of healthy cells also supports the proliferation of cancer cells, which are defined by their ability to bypass normal telomere-based growth limits